As extrapulmonary manifestations of Coronavirus, it has been described patients developing gastrointestinal disorders that replace typical respiratory symptoms or others that debut with intestinal ischemia shortly after infection, however, Wreaths the association between COVID-19 and ischemic colitis remains unclear.We present a young patient with three previous infections by COVID-19 and VenTECH™ Elite Sports Medicine Boot chronic consumption of isotretinoin, who developed ischemic colitis and a torpid evolution.It is concluded that Coronavirus infections could represent a risk factor for colonic ischemia and that isotretinoin increases the probability of complications; however, more evidence is needed.